Does Slight Caloric Restriction Prolong Life?
Reducing calorie intake by just 15% prolongs life, and gives health benefits against chronic disease according to a study published in the journal Cell Metabolism this month. This could be as easy as exchanging a blueberry muffin for an apple at morning tea time, or swapping your regular cappuccino with 1 sugar, for a cup of green or black tea.
Caloric restriction works in the cell by:
1. Stimulating Sirtuins, a family of enzymes that switch our genes on and off
2. Increasing activity of AMPK, an enzyme that helps regulate cellular energy production
3. Reducing mTOR (mechanistic Target Of Rapamycin) a protein associated with faster cellular aging
4. Reducing senescence, which is when ageing cells can no longer divide & promote inflammation
5. Stimulating autophagy, the elimination of old or damaged cells
Certain dietary polyphenols may also help stimulate these factors:
For assistance with identifying a healthy personalized diet for your body call
Sunshine Coast Nutritionist Karen Emans 0408 748 52
Does Slight Caloric Restriction Prolong Life?
Reducing calorie intake by just 15% prolongs life, and gives health benefits against chronic disease according to a study published in the journal Cell Metabolism this month. This could be as easy as exchanging a blueberry muffin for an apple at morning tea time, or swapping your regular cappuccino with 1 sugar, for a cup of green or black tea.
Caloric restriction works in the cell by:
1. Stimulating Sirtuins, a family of enzymes that switch our genes on and off
2. Increasing activity of AMPK, an enzyme that helps regulate cellular energy production
3. Reducing mTOR (mechanistic Target Of Rapamycin) a protein associated with faster cellular aging
4. Reducing senescence, which is when ageing cells can no longer divide & promote inflammation
5. Stimulating autophagy, the elimination of old or damaged cells
Certain dietary polyphenols may also help stimulate these factors:
- Resveratrol a polyphenol in red grapes, berries and red wine has been found to activate Sirtuins along with a cofactor called NAD made in the cell from a type of B3 - Nicotinamide Riboside.
- Hesperidin a flavonoid found in oranges and lemons has also been shown to stimulate AMPK activity, it may thereby improve insulin sensitivity and blood glucose
- Quercetin is a flavonoid that gives pigment to fruits and vegetables may possess senolytic properties, along with theaflavins from black tea
- Resveratrol and Curcumin, have also been shown to stimulate healthy autophagy
For assistance with identifying a healthy personalized diet for your body call
Sunshine Coast Nutritionist Karen Emans 0408 748 52